Flaky and greasy skin in dogs and cats

Flaky and greasy skin in dogs and cats

V-SKIN

SEBO

GLUCOZINC SPRAY

To treat seborrhoeic disorders in dogs and cats, the skin needs to be hydrated and exfoliated, the skin barrier needs to be restored and Malassezia infection controlled.

GlucoZinc spray restores and repairs the skin barrier to maintain dermal homeostasis and the skin´s ecosystem. Its use is helpful for the prevention of relapses.

It is also a good complement for the treatment and prevention of Malassezia dermatitis.

Key points:

  • Contains gluconolactone, a component with keratolytic actions for exfoliation and the reduction of flaking.1, 2, 3, 4, 5
  • With the antibacterial and antifungal action of Zinc.6
  • With Ceramides to restore the epithelium, maintain the barrier function and hydrate the skin.18, 19, 20

When to use it:

  • Leave-on spray that can also be used in areas that are difficult to access such as the interdigital space, to restore the skin balance and gently exfoliate the skin.

How to use it:

  1. Spray on to the desired areas.

Watch the product application video!

Vets' opinions

What you need to know about Seborrheic skin

References

  1. Berardesca E, Distante F, Vignoli GP, Oresajo C, Green B. Alpha hydroxyacids modulate stratum corneum barrier function. Br J Dermatol 1997;137:934-938.
  2. Hachem JP, Roelandt T, Schürer N, Pu X, Fluhr J, Giddelo C, Man M-Q, Crumrine D, Roseeuw D, Feingold KR, Mauro T, Elias PM. Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes. J Invest Dermatol. 2010;130:500-10.
  3. Bernstein EF, Brown DB, Schwartz MD, Kaidbey K, Ksenzenko SM. The polyhydroxy acid gluconolactone protects against ultraviolet radiation in an in vitro model of cutaneous photoaging. Dermatol Surg. 2004;30:189-196.
  4. Puigdemont A, Furiani N, De Lucia M, Carrasco I, Ordeix L, Fondevila D, Ramió-Lluch L, Brazis P. Topical polyhydroxy acid treatment for autosomal recessive congenital ichthyosis in the golden retriever: a prospective pilot study. Vet Dermatol. 2018; 29: 323-e113. May 22. doi: 10.1111/vde.12654
  5. Jarząbek-Perz, S., Mucha, P.; Rotsztejn, H. (2021). Corneometric evaluation of skin moisture after application of 10% and 30% gluconolactone. Skin Research and Technology, (5), 925–930.
    https://doi.org/10.1111/srt.13044
  6. Abendrot, M., & Kalinowska-Lis, U. (2018). Zinc-containing compounds for personal care applications. In International Journal of Cosmetic Science (Vol. 40, Issue 4, pp. 319–327). Blackwell Publishing Ltd.
    https://doi.org/10.1111/ics.12463
  7. Hekmatpou, D., Mehrabi, F., Rahzani, K., & Aminiyan, A. (2019). The effect of aloe vera clinical trials on prevention and healing of skin wound: A systematic review. In Iranian Journal of Medical Sciences (Vol. 44, Issue 1).
  8. Sánchez, M., González-Burgos, E., Iglesias, I., & Gómez-Serranillos, M. P. (2020). Pharmacological update properties of aloe vera and its major active constituents. In Molecules (Vol. 25, Issue 6).
    https://doi.org/10.3390/molecules25061324
  9. Teplicki, E., Ma, Q., Castillo, D. E., Zarei, M., Hustad, A. P., Chen, J., & Li, J. (2018). The effects of aloe vera on wound healing in cell proliferation, migration, and viability. Wounds, 30(9).
  10. Kamr, A., Arbaga, A., El-Bahrawy, A., Elsify, A., Khaled, H., & Hassan, H. (2020). The therapeutic efficacy of Aloe vera gel ointment on staphylococcal pyoderma in dogs. Veterinary World, 13(11).
    https://doi.org/10.14202/VETWORLD.2020.2371-2380
  11. Arbaga, A., El-Bahrawy, A., Elsify, A., Khaled, H., Hassan, H. Y., & Kamr, A. (2021). Biochemical and histopathological changes related to the topical application of Aloe vera ointment for canine pyoderma. Veterinary World, 14(5).
    https://doi.org/10.14202/vetworld.2021.1354-1362
  12. Preethia, K. C., Kuttanb, G; Kuttan, R. (2009). Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian Journal of Experimental Biology 2009 47(2)
  13. Tresch, M., Mevissen, M., Ayrle, H., Melzig, M., Roosje, P.; Walkenhorst, M. (2019). Medicinal plants as therapeutic options for topical treatment in canine dermatology? A systematic review. BMC Veterinary Researc, (1).
    https://doi.org/10.1186/s12917-019-1854-4
  14. Giostri, G. S., Novak, E. M.; Guarita-Souza, L. C. (2021). Treatment of acute wounds in hand with Calendula officinalis L.: A randomized trial. Tissue Barriers.
    https://doi.org/10.1080/21688370.2021.1994822
  15. Cruceriu, D., Balacescu, O; Rakosy, E. (2018). Calendula officinalis: Potential Roles in Cancer Treatment and Palliative Care. In Integrative Cancer Therapies (Vol. 16, Issue 4, pp. 1068–1078). SAGE Publications Inc.
    https://doi.org/10.1177/1534735418803766
  16. Lima, M. dos R., Lopes, A. P., Martins, C., Brito, G. A. C., Carneiro, V. C; Goes, P. (2017). The effect of Calendula officinalis on oxidative stress and bone loss in experimental periodontitis. Frontiers in Physiology, (JUN).
    https://doi.org/10.3389/fphys.2017.00440
  17. John, R.; Jan, N. (2017). Calendula Officinalis-An Important Medicinal Plant with Potential Biological Properties.Proceedings of the Indian National Science Academy,(0).
    https://doi.org/10.16943/ptinsa/2017/49126
  18. ung, J. Y., Nam, E. H., Park, S. H., Han, S. H.; Hwang, C. Y. (2013). Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis. Journal of Veterinary Science, 14(2), 199–205.
    https://doi.org/10.4142/jvs.2013.14.2.199
  19. Reiter, L. v., Torres, S. M. F.; Wertz, P. W. (2009). Characterization and quantification of ceramides in the nonlesional skin of canine patients with atopic dermatitis compared with controls. Veterinary Dermatology, 20(4), 260–266.
    https://doi.org/10.1111/j.1365-3164.2009.00759.x.
  20. Yoon, J. S., Nishifuji, K., Ishioroshi, S., Ide, K.; Iwasaki, T. (2013). Skin lipid profiling in normal and seborrhoeic shih tzu dogs. Veterinary Dermatology, 24(1).
    https://doi.org/10.1111/j.1365-3164.2012.01102.x.