EAR HYGIENE IN DOGS AND CATS

EAR HYGIENE IN DOGS AND CATS

V-SKIN

EAR CLEANER

TRIS-EDTA

Removes purulent ear discharge and bacterial biofilm, leaving the ear ready for application of the otitis treatment. Boosts the effect of antibiotics.

  • Non-ototoxic.
  • Non- irritant, even on sensitive or irritated ear canal epithelium.
  • Suitable for long-term use and to prevent relapses.
  • Alkaline pH.
  • Aqueous and non-greasy formula.
  • Contains a flexible cannula for easier application.

Key points:

When to use it:

To remove purulent secretions in ear infections.

How to use it:

  1. It is recommended that the product should be applied 20-30 minutes before pharmacological ear treatment.

  2. Apply a sufficient quantity to entirely fill the ear canal while holding the ear pinna with the other hand.
    Massage the base of the ear canal for at least 1 minute, so that the product mixes with the purulent discharge, facilitating its removal.

  3. Allow the pet to shake its head in order to expel the mixture of secretion and product from inside the ear canal. Wrap a finger in gauze and clean the opening of the ear canal and the pinna, taking care not to insert it too deeply, in order to avoid causing damage to the animal. Do not use cotton buds. Clean the cannula after each use.

Watch the product application video!

Vets' opinions

What you need to know about Otitis​

References

  1. Chan WY, Hickey EE, Page SW, Trott DJ, Hill PB. Biofilm production by pathogens associated with canine otitis externa, and the antibiofilm activity of ionophores and antimicrobial adjuvants. J Vet Pharmacol Ther. 2019 Nov;42(6):682-692. doi: 10.1111/jvp.12811. Epub 2019 Sep 10. PMID: 31503362.
  2. Nutall 2016. Successful management of otitis externa. In Practice, FOCUS, May 2016: 17.
  3. Chan WY, Khazandi M, Hickey EE, Page SW, Trott DJ, Hill PB. In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa. Vet Dermatol. 2019 Apr;30(2):133-e38. doi: 10.1111/vde.12712. Epub 2018 Dec 13. PMID: 30548715.
  4. Secker B, Shaw S, Atterbury RJ. Pseudomonasspp. in Canine Otitis Externa. Microorganisms. 2023 Oct 28;11(11):2650. doi: 10.3390/microorganisms11112650. PMID: 38004662; PMCID: PMC10673570.
  5. Buckley LM, McEwan NA, Nuttall T. Tris-EDTA significantly enhances antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa in vitro. Vet Dermatol. 2013 Oct;24(5):519-e122. doi: 10.1111/vde.12071. PMID: 24025021.
  6. Finnegan S, Percival SL. EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care. Adv Wound Care (New Rochelle). 2015 Jul 1;4(7):415-421. doi: 10.1089/wound.2014.0577. PMID: 26155384; PMCID: PMC4486448.
  7. Boyd M, Santoro D, Gram D. In vitro antimicrobial activity of topical otological antimicrobials and Tris-EDTA against resistant Staphylococcus pseudintermedius and Pseudomonas aeruginosa isolates from dogs. Vet Dermatol. 2019 Apr;30(2):139-e40. doi: 10.1111/vde.12717. Epub 2019 Jan 23. PMID: 30672043.
  8. Liu Z, Lin Y, Lu Q, Li F, Yu J, Wang Z, He Y, Song C. In vitro and in vivo activity of EDTA and antibacterial agents against the biofilm of mucoid Pseudomonas aeruginosa. Infection. 2017 Feb;45(1):23-31. doi: 10.1007/s15010-016-0905-z. Epub 2016 May 17. PMID: 27189338.
  9. Banin E, Brady KM, Greenberg EP. Chelator-induced dispersal and killing of Pseudomonas aeruginosa cells in a biofilm. Appl Environ Microbiol. 2006 Mar;72(3):2064-9. doi: 10.1128/AEM.72.3.2064-2069.2006. PMID: 16517655; PMCID: PMC1393226.
  10. Cole LK, Luu DH, Rajala-Schultz PJ, Meadows C, Torres AH. In vitro activity of an ear rinse containing tromethamine, EDTA, and benzyl alcohol on bacterial pathogens from dogs with otitis. Am J Vet Res. 2006 Jun;67(6):1040-4. doi: 10.2460/ajvr.67.6.1040. PMID: 16740099.
  11. Farca AM, Nebbia P, Re G. Potentiation of the in vitro activity of some antimicrobial agents against selected gram-negative bacteria by EDTA-tromethamine. Vet Res Commun. 1993;17(2):77-84. doi: 10.1007/BF01839235. PMID: 8212526.
  12. Farca AM, Piromalli G, Maffei F, Re G. Potentiating effect of EDTA-Tris on the activity of antibiotics against resistant bacteria associated with otitis, dermatitis and cystitis. J Small Anim Pract. 1997 Jun;38(6):243-5. doi: 10.1111/j.1748-5827.1997.tb03356.x. PMID: 9200113.
  13. Gotthelf LN. Diagnosis and treatment of otitis media in dogs and cats. Vet Clin North Am Small Anim Pract. 2004 Mar;34(2):469-87. doi: 10.1016/j.cvsm.2003.10.007. PMID: 15062620.